Prevention and Early Detection and Intervention of Post-Coronary Artery Bypass Grafting Surgery (CABG) Acute Kidney Injury (AKI)

Mayo Clinic

Status: Completed

Conditions: Acute Renal Injury; Preventive Measures

Treatments: Procedure: Standard of Care plus Nephrology Care

Study type: Interventional

Funder types: Other

Identifiers

NCT02838667

16-003845

Details and patient eligibility

About

Nephrology participation in care of patients undergoing CABG could reduce AKI through correction of modifiable risk factors and early detection and intervention of post-op AKI.

Enrollment: 2,300 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients (Age >18 years)
• Elective CABG at Mayo Clinic Rochester and Shanghai Zhongshan Hospital from 7/1/2016 to 6/30/2017

Exclusion criteria

• Non-elective CABG
• Renal failure on dialysis
• Renal transplantation

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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2,300 participants in 2 patient groups

Standard of Care

No Intervention group

Description:

If participants are randomized into the non-intervention group, the participants' information during the study period will be collected. Participants will be managed by a care provider as per the standard of care. Participants may receive nephrology consultation as indicated clinically.

Standard of Care plus Nephrology Care

Experimental group

Description:

If participants are randomized into the intervention group, participants' information will be checked by the study investigators daily for 7 days (2 days pre-op and 5 days post-op). When appropriate, investigators may give suggestions to minimize the participants' risk(s) for AKI. Participant's primary care providers may take the suggestions into consideration. Participants' primary care providers are not obligated to carry out the suggestions that are given.

Treatment:

Procedure: Standard of Care plus Nephrology Care