Prevention and Treatment of Laryngospasm and Hypoxemia Based on Risk Factors in Adult Outpatients Undergoing EGD

Envision Healthcare Scientific Intelligence

Status: Completed

Conditions: Laryngospasm; Hypoxemia

Treatments: Other: Prophylactic suctioning when clinically indicated

Study type: Interventional

Funder types: Other

Identifiers

NCT04159116

TRE2019-EGD01

Details and patient eligibility

About

The purpose of this study is to identify patient and provider-chosen factors that put patients at risk for the development of hypoxemia (oxygen saturation < 90% for 5 seconds) during endoscopy and to use this knowledge to develop a treatment protocol for specific causes of hypoxemia in adult esophagogastroduodenoscopy outpatients.

Enrollment: 57 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Over the age of 18 years
• English speaking
• Mentally competent to sign their own consent for treatment

Exclusion criteria

• Poor incisor teeth stability
• Anticipated procedure of greater than 30 minutes
• History of facial or oral surgery and a baseline oxygen saturation of less than 95% on room air

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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57 participants in 2 patient groups

Suctioned Prior to Endoscope

Experimental group

Description:

This group will be suctioned prophylactically after sedation but prior to introduction of endoscope.

Treatment:

Other: Prophylactic suctioning when clinically indicated

Standard of Care

Other group

Description:

This group will be suctioned by anesthesia providers when clinically indicated by copious secretions, coughing, choking or desaturation.

Treatment:

Other: Prophylactic suctioning when clinically indicated