Prevention and Treatment of Perioperative Lung Injury in Elderly Patients

Huazhong University of Science and Technology

Status: Not yet enrolling

Conditions: Postoperative Pulmonary Complications; Elderly Patients

Study type: Observational

Funder types: Other

Identifiers

NCT05701449

PPCS192023

Details and patient eligibility

About

This study aims to verify the prediction model of postoperative pulmonary complications by collecting clinical information on elderly patients. In addition, the incidence of postoperative pulmonary complications in elderly patients before and after using the prediction model was compared.

Full description

More than 300 million major operations are performed worldwide each year, and older patients account for about a third of elective operations. Compared with young people, the elderly are more prone to postoperative complications due to age-related degeneration of the physiological functions of various organs and tissues. Postoperative pulmonary complications, including pneumonia, atelectasis, and respiratory failure, are common. Even mild pulmonary complications can lead to the prolonged hospital stay and increased postoperative mortality.

Although there have been many studies on postoperative lung complications, there have been few studies on elderly patients. In our country, the real incidence data of elderly patients after a perioperative period of pulmonary complications, the lack of effective prevention, intervention measures, and targeted prevention and treatment technology, these reasons lead to the clinical diagnosis and treatment of elderly patients after a perioperative period of pulmonary complications are very difficult. Therefore, the research team intends to verify the established prediction model of postoperative pulmonary complications and compare the incidence of postoperative pulmonary complications in elderly patients before and after using the prediction model.

Enrollment: 5,000 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 65 years or older
2. receiving invasive ventilation during general anesthesia for surgery

Exclusion criteria

1. preoperative mechanical ventilation
2. procedures related to a previous surgical complication
3. a second operation after surgery within one week
4. organ transplantation
5. discharged within 24 hours after surgery

Trial design

5,000 participants in 2 patient groups

Patients applying a prediction model for postoperative pulmonary complications

Patients non-applying a prediction model for postoperative pulmonary complications