Prevention of Acute Mountain Sickness by Intermittent Hypoxia

Heidelberg University

Status: Completed

Conditions: Acute Mountain Sickness

Treatments: Other: Hypoxic Exposure

Study type: Interventional

Funder types: Other

Identifiers

NCT00559832

039/2006

Details and patient eligibility

About

Acclimatization by mountaineering prior to high altitude sojourns have shown to be effective in prevention of acute mountain sickness (AMS).

The aim of this study is to investigate whether intermittent exposure to normobaric hypoxia during sleep is also effective to prevent AMS.

Enrollment: 75 patients

Sex: Male

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy

Exclusion criteria

• Altitude exposure above 2000 m 8 weeks prior or during the study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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75 participants in 2 patient groups

Normoxia

No Intervention group

Description:

Sleeping in normoxia for 14 nights prior to one night at 4500 m

Hypoxia

Experimental group

Description:

Sleeping in normobaric hypoxia for 14 nights at altitudes from 2500 - 3300 m prior to one night at 4500 m

Treatment:

Other: Hypoxic Exposure