Prevention of Cardiovascular Diseases Caused by Complex Treatment of Patients With Primary Operated Breast Cancer

State Institution "Republican Scientific and Practical Center" Cardiology, Belarus

Status and phase: Completed; Phase 2

Conditions: Women With Breast Cancer

Treatments: Drug: Bisoprolol; Perindopril;

Study type: Interventional

Funder types: Other

Identifiers

NCT04588935

20192755

Details and patient eligibility

About

To develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

Full description

Purpose of the study: to develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

Enrollment: 100 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• women with breast cancer, with a morphologically confirmed diagnosis before the appointment of anticancer therapy.

Exclusion criteria

• presence of other oncological diseases

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

Group 1

No Intervention group

Description:

women with breast cancer, with a morphologically confirmed diagnosis before the appointment of anticancer therapy, untreated

Group 2

Active Comparator group

Description:

women with breast cancer, with a morphologically confirmed diagnosis before the appointment of anticancer therapy, receiving treatment with a combination of bisoprolol and perindopril

Treatment:

Drug: Bisoprolol; Perindopril;