Prevention of Energy Deficit Syndrome in Female Athletes. Molecular Mechanisms Associated With Malnutrition.

University of Alicante

Status: Completed

Conditions: Female Athlete Triad; Antioxidative Stress; Energy Deficit Syndrome; Red Fruits; Nutritional Disorder; Sports Physical Therapy; Mediterranean Diet

Treatments: Other: Personalized nutritional planning based on the Mediterranean diet + physical exercise + use of mobile application.; Other: Free use of the virtual platform.; Other: Personalized nutritional planning with an extra intake of berries + physical exercise + use of mobile application.

Study type: Interventional

Funder types: Other

Identifiers

NCT05567211

UA-2021-03-11

Details and patient eligibility

About

Energy Deficit Syndrome (RED-S) is the impairment of physiological functioning caused by relative energy deficiency and includes impaired metabolic rate, menstrual, endocrine, hematological, immunological, gastrointestinal, bone, psychological, developmental and cardiovascular function. Eighty-seven percent of athletes show at least one symptom related to RED-S, with a higher prevalence in women. Treatment of RED-S preferably involves a multidisciplinary team of health professionals to address the complex interaction of nutrition, training, body image and performance. The main objective is to prevent energy deficit syndrome in female athletes in the province of Alicante through different training and diet protocols using a virtual platform. A 12-week single-blind randomized clinical trial with an intervention period and a control period (RCT) is proposed. The sports federations of the most representative practices in the province of Alicante will be selected by randomized sampling. The female athletes will be randomly divided into 4 groups (control group; control group with free use of the virtual platform; intervention group with Mediterranean diet and physical exercise planning; intervention group with red fruits and physical exercise planning).

Enrollment: 50 patients

Sex: Female

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• (a) exercise at least 3 days/week,
• (b) not having any diagnosed chronic pathology or ailment that prevents physical exercise or following nutritional guidelines rich in antioxidants.

Exclusion criteria

• All individuals taking medication that could affect the results of the study will be excluded from the study.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 4 patient groups, including a placebo group

Control group

No Intervention group

Description:

Will receive basic recommendations from the World Health Organization on healthy eating and physical activity.

Control group with free use of the virtual platform

Placebo Comparator group

Description:

The athletes, in addition to the recommendations indicated in the previous point, will have access to the virtual platform designed to voluntarily record the parameters they consider appropriate.

Treatment:

Other: Free use of the virtual platform.

Intervention group with Mediterranean diet and physical exercise planning

Active Comparator group

Description:

They will receive nutritional plans adapted to their energy expenditure and based on Mediterranean diet. The physical exercise intervention will be based on 3 weekly sessions of 50 minutes of combined resistance and strength, deferred.

Treatment:

Other: Personalized nutritional planning based on the Mediterranean diet + physical exercise + use of mobile application.

Intervention group with red berries and physical exercise planning

Active Comparator group

Description:

They will also receive personalized nutritional plans with a diet rich in antioxidants obtained from red berries and the same physical exercise intervention as in the Mediterranean diet intervention group.

Treatment:

Other: Personalized nutritional planning with an extra intake of berries + physical exercise + use of mobile application.