Prevention of Functional and Cognitive Impairment in Hospitalized Oncogeriatric Patients

Fundacion Miguel Servet

Status: Completed

Conditions: Aging; Hospital Acquired Condition; Debility; Cancer

Treatments: Behavioral: Multicomponent exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT05424055

ONCOGERI-ACUTE

Details and patient eligibility

About

Hospitalized older patients usually remain bedridden for many hours and this may lead to the appearance of unwanted negative consequences, such as cognitive or physical decline upon discharge. Our study will analyze whether an intervention consisting of a multicomponent training programme applied to patients over the age of 60 who are hospitalized for acute medical conditions in an Oncology Department of a tertiary hospital improves functional capacity and cognitive function. A total of 50 hospitalized older adult patients will be recruited in the Hospital Universitario de Navarra, Pamplona, Spain. The participants will be randomized and included in an exercise intervention (n = 25) or a control (n = 25) group (hospital usual-care). The intervention consists of a multicomponent exercise training programme that will take place for 3 consecutive days (2 sessions/day). The control group will receive usual hospital care, which will include physical rehabilitation when needed. Functional and cognitive impairment after and during acute hospitalization in older adults are major determinants of the later need for health resources. If our hypothesis is correct and shows that a multicomponent, individualized and progressive exercise programme is an effective therapy for improving the functional capacity of acutely hospitalized older patients compared to usual care, a change in the current system of hospitalization may be justified in oncogeriatric patients with medical conditions

Enrollment: 58 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 65 years
• Barthel Index ≥60 points
• Able to ambulate (with/without assistance)
• Sign the informed consent
• Able to communicate

Exclusion criteria

• Expected length of stay < 6 days
• Terminal illness
• Very severe cognitive decline (i.e., GDS 7)
• Uncontrolled arrhythmias, acute pulmonary embolism, acute myocardial infarction or limb bone fracture in the past 3 months.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Sequential Assignment

Masking: Triple Blind

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58 participants in 2 patient groups

Multicomponent Exercise

Experimental group

Description:

The intervention will consist of a multicomponent exercise training programme, which will include supervised progressive resistance exercise training, balance training, and walking for 3 consecutive days. During the training period, patients will be trained in 20-minute sessions twice a day (morning and evening).

Treatment:

Behavioral: Multicomponent exercise

Usual care

No Intervention group

Description:

Participants randomly assigned to the usual care group will receive normal hospital care, including physical rehabilitation when needed