Prevention of Healthcare Associated Infections in Bone Marrow Transplant Patients

University of British Columbia

Status: Completed

Conditions: Transplantation Infection

Treatments: Other: Engineered Room

Study type: Interventional

Funder types: Other

Identifiers

NCT02463214

H15-00662

Details and patient eligibility

About

This study involves sampling bone marrow transplant patients, hospital workers and the patient room for microbes using swabs and other techniques. We send these samples to the laboratory, where they will use state-of-the art technology to identify and relate the microbes to each other. This study also involves putting copper, nickel, or titanium into some hospital rooms, and seeing whether these metals influences the growth of microbes. Some equipment in the hospital room, such as faucets and soap dispensers will be replaced by sensor-based (e.g. touchless) controls.

Full description

Bacteria and other microbes are everywhere, the majority of which are harmless. They live on our bodies, on everyday objects, in food, and in our environment. They are passed around through the many interactions with other people and our surroundings. Some are even beneficial, helping us digest our food or protecting us from infections caused by harmful microbes.

In rare instances, some of the harmful microbes can cause infections. When a microbe causes an infection while we are in healthcare facilities, they are called "Healthcare-associated infections", or "HAIs". Examples that you may have heard of include Clostridium difficile, and MRSA (methicillin-resistant Staphylococcus aureus). Vancouver General Hospital already has some of the lowest HAI rates in the country. We have dedicated hospital workers that do a great job at preventing HAIs, but we are always looking for ways to be even better.

Enrollment: 45 patients

Sex: All

Ages: 19 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria (Patients):

• undergoing allogenic bone marrow transplant for acute myeloid leukemia
• will be admitted to the leukemia and bone marrow transplant service at Vancouver General Hospital
• admission to the ward anticipated to be approximately 28 days

Exclusion Criteria (Patients):

• allergies to copper, nickel or titanium
• patients admitted for stays anticipated to be less than 28 days

Inclusion Criteria (Health care worker):

• undergoing allogenic bone marrow transplant for acute myeloid leukemia
• caring for patient enrolled in the study as a primary nurse

Exclusion Criteria (Health care worker):

• allergies to copper, nickel or titanium

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

45 participants in 2 patient groups

Standard Room

No Intervention group

Description:

Standard bone marrow transplant recovery, single occupancy, room

Engineered Room

Experimental group

Description:

Single occupancy bone marrow transplant recovery room, engineered with touchless devices, and surfaces coated with either copper or titanium dioxide.

Treatment:

Other: Engineered Room