Prevention of Human Papillomavirus (HPV) Infection in Paediatric Kidney and Liver Transplant Recipients and in Paediatric Patients With Advanced Chronic Kidney Disease

University Hospital Heidelberg

Status: Unknown

Conditions: Chronic Kidney Disease; Paediatric Kidney or Liver Transplantation

Study type: Observational

Funder types: Other

Identifiers

NCT03100682

HPVaxResponse Study

Details and patient eligibility

About

Due to their immunosuppressive therapy, solid-organ transplant (SOT) recipients bear a 10 to 100 times higher risk of human papillomavirus (HPV)-associated malignancies than healthy individuals. The objectives of this observational, non-interventional multi-national, multi-centre research project are to gain an insight into current HPV vaccination strategies and to investigate the immune response to different routinely administered HPV vaccines in European paediatric SOT candidates and immunocompromised transplant recipients, enabling patients at risk of vaccination failure to be identified.

Enrollment: 140 estimated patients

Sex: All

Ages: 9+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Paediatric Kidney and/or Liver transplant recipients
• Paediatric patients with CKD
• Who receive HPV vaccination according to country-specific vaccine schedule

Exclusion criteria

• No HPV vaccination according to country-specific vaccine schedule
• No written informed consent