Prevention of Intradialytic Hypotension in Acute Kidney Injury Patients

Sao Jose do Rio Preto Medical School

Status: Completed

Conditions: Acute Kidney Injury; Acute Renal Failure

Treatments: Procedure: Dialysis; Procedure: Standard SLED

Study type: Interventional

Funder types: Other

Identifiers

NCT00971971

10727-6

Details and patient eligibility

About

Intradialytic hypotension (IH) is a major complication during acute hemodialysis. The aim of this study was to evaluate the effects of dialysate temperature (DT) reduction with Na and ultrafiltration (UF) profiling on hemodynamics of critically ill acute kidney injury (AKI) patients submitted to sustained low-efficiency dialysis (SLED).

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute renal failure with a need of dialysis.

Exclusion criteria

• Patients with basal serum creatinine > 3 mgdL.
• Patients submitted to renal transplantation.
• Patients unlikely to survive.
• Declination in authorization to participation in the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Control

No Intervention group

Description:

Traditional SLED

Treatment:

Procedure: Standard SLED

Profiling

Experimental group

Description:

dialysate temperature reduction with Na and ultrafiltration (UF) profiling

Treatment:

Procedure: Dialysis