Prevention of Ovarian Cancer in Women Participating in Mammography

Fred Hutchinson Cancer Center (FHCC)

Status

Completed

Conditions

Epithelial Ovarian Cancer

Treatments

Behavioral: genetic counseling

Study type

Interventional

Funder types

Other

Identifiers

NCT01851109

1R18DP001142-01

Details and patient eligibility

About

The primary purpose of this study is to evaluate the effect of systematic identification and genetic counseling referral on rates of bilateral salpingo-oophorectomy (surgery to remove both fallopian tubes and ovaries) in women having mammograms at Swedish Medical Center in Seattle, WA.

Enrollment

458 patients

Sex

Female

Ages

35+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Prior mammogram at Swedish Medical Center
Willing and able to provide informed consent, primary physician information, and complete study questionnaires
Must meet at least ONE of the following criteria:
personal history of breast cancer diagnosed before age 50
personal history of bilateral breast cancer at any age
1 or more first degree relatives with breast cancer diagnosed before age 50
3 or more first or second degree relatives with breast cancer at any age
2 second degree relatives with breast cancer diagnosed before age 50
A male relative with breast cancer at any age
Ashkenazi Jewish with any family history of breast or ovarian cancer
1 first or second degree relative with ovarian cancer AND 1 first or second degree relative with breast cancer at any age
2 first degree relatives with ovarian cancer or 2 second degree relatives with ovarian cancer or 1 first and 1 second degree relative with ovarian cancer.
A first degree relative with both breast and ovarian cancer (2 primaries in the same person)
Personal history of positive genetic test result for any of the following genes: BRCA1, BRCA2, HNPCC, or P53
Family history of a positive genetic test result for any of the following genes: BRCA1, BRCA2 or HNPCC