Prevention of Postpartum Haemorrhage

Benha University

Status: Unknown

Conditions: Post Partum Hemorrhage

Treatments: Drug: Tranexamic acid injection

Study type: Interventional

Funder types: Other

Identifiers

NCT04463966

Tranexamic

Details and patient eligibility

About

Use of Tranexamic Acid for prevention of Postpartum hemorrhage in high risk patients: Randomized Control Trial

Full description

This study aims to assess the efficacy of administration of Tranexamic Acid in preventing Postpartum haemorrhage & reducing intraoperative and postoperative blood loss in high risk women for Postpartum Hemorrhage undergoing caesarean section. Studying its benefit to transfusion-sparing and hysterectomy-sparing. & reduction of hemorrhage-related mortality when Postpartum hemorrhage is expected.

Enrollment: 100 estimated patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women at high risk for postpartum hemorrhage after cesarean section

Exclusion criteria

• women who are not at high risk for postpartum hemorrhage , or attending for normal vaginal delivery.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

Study

Active Comparator group

Description:

Tranexamic acid 1 gm (100 mg/ml) slowly intravenous infusion during delivery ( administered over 10 minutes at 1 ml/minute) .

Treatment:

Drug: Tranexamic acid injection

Control

No Intervention group

Description:

control group will not be given tranexamic acid