Prevention or Treatment of Arterial Hypotension and Oxygen Cerebral Saturation During Major Abdominal Surgery

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Completed

Conditions: Hemodynamic Instability; Hypotension During Surgery

Treatments: Device: HPI

Study type: Interventional

Funder types: Other

Identifiers

NCT05481047

5079 (Other Identifier)

Details and patient eligibility

About

In this study investigators will explore the association between intraoperative arterial hypotension and cerebral oxygen saturation in patients scheduled for major abdominal surgery. Investigators will assign patients to control or interventional group. In this last group arterial hypotension will be avoided based on a HPI (Hypotension Predictive Index) protocol. In the control group arterial hypotension will be promptly treated according to hemodynamic variables.

Enrollment: 48 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled for abominal surgery

Exclusion criteria

• Emergency surgery
• end-stage renal disease
• pregnancy
• obesity
• atrial fibrillation
• previous cerebral ischaemia
• central nervous system disorders
• severe cardiac valvular disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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48 participants in 2 patient groups

prevention

Experimental group

Description:

investigator will prevent intraoperative arterial hypotension based on HPI index

Treatment:

Device: HPI

treatment

No Intervention group

Description:

investigators will treat intraoperative arterial hypotension based on standard hemodynamic parameters