Preventive Anti-inflammatory Diet to Reduce Gastro-intestinal Inflammation in FAP Patients: a Prospective Pilot Study (FAPPER)

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Status: Completed

Conditions: Familial Adenomatous Polyposis (FAP)

Treatments: Dietary Supplement: Anti-inflammatory Diet

Study type: Interventional

Funder types: Other

Identifiers

NCT04552405

INT 78/17

Details and patient eligibility

About

Preventive anti-inflammatory diet to reduce gastro-intestinal inflammation in FAP patients: a prospective pilot study

Full description

a prospective pilot study

Enrollment: 35 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• FAP patients carrying mutations in APC gene, submitted to prophylactic total colectomy/IRA (with rectum preservation) and that participate to the regular endoscopic surveillance program at IRCCS-INT.

Exclusion criteria

• FAP patients taking NSAIDs and/or Omega 3
• Patients who carried MUTYH germline mutations or had no APC mutation found.

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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35 participants in 1 patient group

FAP patients

Other group

Description:

FAP patients who underwent prophylactic total colectomy

Treatment:

Dietary Supplement: Anti-inflammatory Diet