Preventive Effect of H.pylori Eradication on Osteoporosis

Seoul National University

Status: Completed

Conditions: Osteoporosis; HELICOBACTER PYLORI INFECTIONS

Treatments: Diagnostic Test: DEXA(Dual-Energy X-ray Absorptiometry)

Study type: Observational

Funder types: Other

Identifiers

NCT06818591

B-2401-878-002

Details and patient eligibility

About

In this study, the investigators observed the long-term incidence rate of osteoporosis in patients who received Helicobacter pylori eradication and examined differences by age and sex.

Full description

In this study, the investigators observed the long-term incidence rate of osteoporosis in patients who received Helicobacter pylori eradication and examined differences by age and sex. In addition, the investigators will analyze the correlation between the incidence of osteoporosis by comparing confounding factors such as body mass index, steroid use, and proton pump inhibitor use as well as the eradication status of H. pylori.

Enrollment: 846 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

ㆍPatients tested Helicobacter pylori status

Exclusion criteria

ㆍPatients aged < 20 years ㆍPatients with unknown Helicobacter pylori bone density status ㆍPatients with with a history of gastric cancer ㆍPatients with prior Helicobacter pylori eradication therapy ㆍPatients with a history of osteoporosis

Trial design

846 participants in 2 patient groups

Eradicated group

Description:

Helicobacter pylori eradication was successfully achieved.

Treatment:

Diagnostic Test: DEXA(Dual-Energy X-ray Absorptiometry)

Non-eradicated group

Description:

Helicobacter pylori eradication was not successfully achieved.

Treatment:

Diagnostic Test: DEXA(Dual-Energy X-ray Absorptiometry)