PRF for Treating Maxillary Gingival Recession

Arab American University (Palestine)

Status: Completed

Conditions: Gingival Recession

Treatments: Procedure: Gingival coverage using coronally advanced flap and platelet rich fibrin membranes; Procedure: Gingival coverage using coronally advanced flap and a connective tissue graft

Study type: Interventional

Funder types: Other

Identifiers

NCT05267015

ArabAmericanU

Details and patient eligibility

About

This is a split-mouth, randomized, controlled clinical trial that aims to evaluate the clinical efficacy of platelet-rich fibrin (PRF) membranes in conjunction with coronally advanced flap (CAF) in treating maxillary gingival recession defects.

Enrollment: 15 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Greater than 18 years old
• Bilateral Miller class I + II recession in the upper jaw

Exclusion criteria

• Smokers
• Patients with systemic diseases that could interfere with the healing
• Patients undergoing bisphosphonate therap .Patients who previously received radiation therapy of the jaws.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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15 participants in 2 patient groups

coronally advanced flap with connective tissue graft

Active Comparator group

Description:

After randomization a subepithelial connective tissue graft along with coronally advanced flap is applied to one maxillary quadrant to cover the recession.

Treatment:

Procedure: Gingival coverage using coronally advanced flap and a connective tissue graft

coronally advanced flap with platelet rich fibrin membranes

Experimental group

Description:

After randomization platelet rich fibrin membranes along with coronally advanced flap are applied to the other maxillary quadrant to cover the recession.

Treatment:

Procedure: Gingival coverage using coronally advanced flap and platelet rich fibrin membranes