Primary Anatomical Versus Primary Electrophysiological Approach in Circumferential Pulmonary Vein Ablation (CPVA-PAF)

University Hospital Bonn (UKB)

Status: Unknown

Conditions: Paroxysmal Atrial Fibrillation

Treatments: Procedure: primary anatomical approach; Procedure: primary electrophysiological approach

Study type: Interventional

Funder types: Other

Identifiers

NCT00556595

IRB 160/07

CPVA-PAF

Details and patient eligibility

About

Randomized comparison between 2 techniques of circumferential pulmonary vein ablation in paroxysmal atrial fibrillation: Primary anatomical ablation with secondary closure of possible electrical gaps versus primary electrophysiological ablation at the sites of atrio-venous electrical breakthroughs with secondary circumferential ablation around the pulmonary vein orifice

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• paroxysmal atrial fibrillation
• age over 18 years

Exclusion criteria

• persistent atrial fibrillation
• reversible cause of atrial fibrillation
• inability to comply with follow-up

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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200 participants in 2 patient groups

1

Experimental group

Description:

primary electrophysiological approach

Treatment:

Procedure: primary electrophysiological approach

2

Active Comparator group

Description:

primary anatomical approach

Treatment:

Procedure: primary anatomical approach