Primary Colorectal Signet Ring Cell Carcinoma and the Risk of Multiple Primary Gastrointestinal Malignancies

asmaa salama ibrahim

Status: Completed

Conditions: Colorectal Carcinoma; Signet Ring Adenocarcinoma of the Colon; Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT06978595

Z2730

Details and patient eligibility

About

This original research investigates the critical issue of gastrointestinal (GI) second primary malignancies (SPMs) in patients with signet ring cell carcinoma (SRCC), a rare and aggressive subtype of colorectal cancer. Utilizing the Surveillance, Epidemiology, and End Results (SEER) database, the investigators assessed the risk of GI SPMs, particularly within 2-11 months post-SRCC diagnosis.

Enrollment: 8,171 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with primary colorectal SRCC between 2000 and 2021
• Latency exclusion period of two months

Exclusion criteria

• patients with unknown age data