Primary Immunodeficiencies and Obstetrical Neuraxial Anaesthesia (ANEU-DIP)

Assistance Publique - Hôpitaux de Paris

Status: Completed

Conditions: Obstetrical Neuraxial Anaesthesia; Infectious Complications (Epidural Abscess or Meningitis)

Treatments: Other: Non applicable

Study type: Observational

Funder types: Other

Identifiers

NCT06449066

APHP240481

Details and patient eligibility

About

The purpose of this study is to evaluate if neuraxial anesthesia (epidural or intradural anesthesia) used during childbirth is associated with more frequent infectious complications in patients with primary immunodeficiencies (PID).

Full description

Neuraxial anaesthesia (epidural or intradural) is often used to alleviate pain during labour and childbirth. Although extremely efficient and safe, rare but serious infectious complications such as epidural abscess or meningitis can occur afterwards.

Patients with PID tend to have a greater risk of infectious complications than the general population. With the progress of medical care in those pathologies, female patients are now giving birth more often. The use of neuraxial anaesthesia and the associated infectious complications have never been studied in this population.

The investigators intend to review the medical records of PID patients who gave birth in an APHP hospital in the last 10 years to evaluate the use of neuraxial anesthesia and the frequency of infectious complications associated with neuraxial anesthesia.

Enrollment: 30 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female patient included in the CEREDIH national register
• Aged > 18 years

Exclusion criteria

• Refuse to participate
• Deceased
• Minor
• under judicial protection
• obstetric file not available

Trial design

30 participants in 1 patient group

Patients

Description:

CEREDIH (centre de reference des deficits immunitaires héréditaires) cohort Female patients, alive and \> 18 years old, registered at the CEREDIH who gave birth in an APHP maternity

Treatment:

Other: Non applicable