Priorities Aligned Deprescribing for Persons Living With Dementia and Their Caregiver

The University of Texas System (UT)

Status: Completed

Conditions: Dementia

Treatments: Behavioral: PPC; Behavioral: Usual care

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05970315

HSC-SPH-22-0639

5R24AG064025-05 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to compare patient priorities care (PPC) and usual care (UC) patients to identify differences in post-encounter medication changes, treatment burden (TBQ), and shared decision making in Older Patient Assessment of Chronic Illness Care (OPACIC), to understand PPC participant's sense-making and communication approaches related to deprescribing decisions in relation to the identified health priorities and to identify and categorize adverse drug withdrawal events (ADWEs)

Enrollment: 45 patients

Sex: All

Ages: 55+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Dementia listed as an active problem in the medical record, including Alzheimer's disease, vascular dementia, frontotemporal dementia, Parkinson's dementia, Lewy body disease.
• The functional assessment staging tool (FAST) score of 5 or lower (This will be established by the patient's clinician).
• 2 or more additional chronic conditions
• Takes 5 or more regular medications and
• A caregiver present during visits. Caregivers may include family members or unrelated caregivers and will be identified through chart review and confirmed by clinician, patient, and surrogate decision maker if necessary. Identified caregivers must be involved in decisions and care of People living with dementia (PLWD) and routinely attend clinic visits with patient

Exclusion criteria

• FAST score of 6 or more (This will be established by the patient's clinician).
• Significant hearing, vision, or advanced cognitive impairment that limits ability to participate in PPC encounters,
• Caregiver is unwilling or able to participate in visits, or
• Deemed ineligible by their Primary care physician (PCP)

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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45 participants in 2 patient groups

PPC

Experimental group

Treatment:

Behavioral: PPC

Usual Care

Active Comparator group

Treatment:

Behavioral: Usual care