Priority to Cryopreservation Strategy (PCS) in IVF-ICSI Cycles

Tanta University

Status: Enrolling

Conditions: IVF; Infertility; Cryopreservation; ICSI

Treatments: Procedure: Fresh embryo transfer; Procedure: Priority to freeze

Study type: Interventional

Funder types: Other

Identifiers

NCT03913208

PCS

Details and patient eligibility

About

This multicentre randomized controlled trial will be done to evaluate a new strategy in IVF-ICSI practice that gives that priority to freeze for the embryos and goes to fresh embryo transfer only if at least one set of same quality embryos is available for cryopreservation.

Full description

This study will be a non-blind, prospective, double-armed, randomized clinical trial. The study will be conducted at five centers, the Educational Hospital Fertility Unit of Tanta University, the fertility center of Cairo University, the fertility center of Assiut University, the Egyptian Consultants Fertility Center in Tanta, and MRC fertility center in Cairo from May 1st 2019 till the end of the objected number. The study will be conducted in accordance with the Declaration of Helsinki, and all participants should sign a written informed consent before inclusion in the study.

Enrollment: 1,000 estimated patients

Sex: Female

Ages: 20 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Candidates for IVF/ICSI
• Presence of good number of embryos > 5

Exclusion criteria

• Low quality embryos
• Low ovarian reserve
• Low number of embryos

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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1,000 participants in 2 patient groups

Study group

Experimental group

Description:

Will be subjected to priority to freeze

Treatment:

Procedure: Priority to freeze

Control group

Active Comparator group

Description:

Will receive fresh embryo transfere

Treatment:

Procedure: Fresh embryo transfer