Prism Adaptation Therapy for Spatial Neglect

Kessler Foundation

Status: Unknown

Conditions: Spatial Neglect; Deficits in Attention Motor Control and Perception

Treatments: Behavioral: Prism Adaptation Treatment

Study type: Interventional

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT00989430

AMBarrett3

Spatial Neglect (Other Grant/Funding Number)

Details and patient eligibility

About

The purpose of this research study with a randomized controlled design is to examine the effects of prism adaptation treatment on two visual-spatial recovery components. After a stroke, an "internal GPS", locating where objects or people lie in a particular area of space, may be impaired. Alternately, a stroke may impair precise visual-spatial hand and body aiming movements. The research team wishes to discover whether prism adaptation treatment (two weeks of daily 20-min sessions of goal-directed movement with prism goggles) affects visual-spatial where or aiming errors selectively after stroke.

This research represents one of the first attempts to apply what we know about the brain from neuroscience research, to modern clinical rehabilitation practices.

Full description

The purpose of this research study with a randomized controlled design is to examine the effects of prism adaptation treatment on two visual-spatial recovery components. After a stroke, an "internal GPS", locating where objects or people lie in a particular area of space, may be impaired. Alternately, a stroke may impair precise visual-spatial hand and body aiming movements. The research team wishes to discover whether prism adaptation treatment (two weeks of daily 20-min sessions of goal-directed movement with prism goggles) affects visual-spatial where or aiming errors selectively after stroke.

This research represents one of the first attempts to apply what we know about the brain from neuroscience research, to modern clinical rehabilitation practices.

Enrollment: 160 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The subject is 18 to 100 years of age, inclusive.
• The subject has had a stroke on the right side of the brain.
• The subject is able to give Informed consent.
• The subject has a spatial neglect (if known).
• The subject is able and willing to comply with the study protocol, including availability for all scheduled clinic visits.

Exclusion criteria

• The subject has or had a serious brain condition other than stroke.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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160 participants in 2 patient groups

Prism Adaptation Treatment

Experimental group

Description:

Two weeks of prism adaptation treatment followed by 4 weekly assessments and long-term follow-ups at the 3rd and 6th months.

Treatment:

Behavioral: Prism Adaptation Treatment

Control: Standard Rehabilitation Care

No Intervention group

Description:

Participants will continue with their standard inpatient rehabilitation care. They will be assessed with cognitive and functional scales for tracking their recovery.