Probiotic Administration and Perennial Allergic Rhinitis

Nestlé

Status

Completed

Conditions

Rhinitis, Allergic, Perennial

Treatments

Dietary Supplement: Lactobacillus paracasei probiotic strain

Dietary Supplement: Placebo

Study type

Interventional

Funder types

Industry

Identifiers

NCT01779895

12.18.MET

Details and patient eligibility

About

The purpose of this study is to evaluate the efficacy of a probiotic strain in improving the quality of life in adult subjects suffering from perennial allergic rhinit.

Enrollment

64 estimated patients

Sex

All

Ages

20 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Adults between 20-65 years old
Confirmed allergy (allergic rhinitis) to dust mite for more than 2 years, as determined by anamnesis and by a miniRQLQ of ≥ 1
Positive Skin prick testing measure greater than 3mm wheal diameter to the dermatophagoides pteronyssinus species of house dust mite extract
Body Mass Index 19-29
Having obtained his/her informed consent

Exclusion criteria

Anemia
Allergy to any food or medication
Asthma
Family history of congenital immunodeficiency or chronic consumption (more than one week at Screening) of immunosuppressive or anti-inflammatory treatments
Ongoing treatment with antibiotics or undergoing allergen immunotherapy at Screening
Consumption of probiotic and other dietary nutritional interventions
More than 2 drinks/day alcohol consumption or use of illicit drugs
Pregnant women
Subjects with expected low compliance
Blood donation in the past month or planning to donate blood until a month after the end of the study
Currently participating or having participated in another interventional clinical trial during the last four weeks prior to the beginning the study