Probiotic Sport Study

Green Beat

Status: Completed

Conditions: Inflammation; Oxidative Stress; Endotoxemia

Treatments: Dietary Supplement: placebo; Dietary Supplement: probiotic-based dietary supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT01474629

23-509 ex 10/11

Details and patient eligibility

About

We investigate the impact of a probiotic-based dietary supplement on oxidative stress and endotoxemia before and after strenuous exercise.

Hypotheses (H1):

• Supplementation has an influence on oxidative stress parameters before and post exercise
• Supplementation has an influence on parameters of endotoxemia and inflammation before and post exercise
• Strenuous exercise has an influence on parameters of oxidative stress, inflammation and endotoxemia

Enrollment: 24 patients

Sex: Male

Ages: 30 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• trained men
• 30 - 45 years
• non-smokers
• 4wk wash out of all dietary supplements

Exclusion criteria

• untrained people (VO2max < 55 ml x kg-1)
• female
• all people not matching this age group
• smokers
• all men taking dietary supplements
• all men that fail in ergometric exercise eligibility testing, refering to the standards in sports medicine (e.g.: significant ST-decrease or increase, blood pressure > 240 mmHg, tachycardia, polymorphic extrasystolia, cyanosis, bradyarrhythmia..)
• all people that are not adjudged as "Healthy"

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

24 participants in 2 patient groups, including a placebo group

probiotic-based dietary supplement

Active Comparator group

Treatment:

Dietary Supplement: probiotic-based dietary supplement

placebo

Placebo Comparator group

Treatment:

Dietary Supplement: placebo