Probiotics and Overreaching Recovery

University of Padova

Status: Unknown

Conditions: Fatigue; Muscle, Heart; Immunosuppression

Treatments: Dietary Supplement: placebo; Dietary Supplement: probiotics

Study type: Interventional

Funder types: Other

Identifiers

NCT04885010

PARIS

Details and patient eligibility

About

Overloading is a key training principle used by athletes and coaches to improve physical performance. Intensified training periods are therefore commonly incorporated into the course of a regular training season. From a clinical point of view, very intense periods of training are associated with a temporary immunological deficiency which can lead to teh "overreaching syndroms".

During periods of overreaching, nutritional strategies are mainly aimed at ensuring sufficient amounts of energy to support the increase in effort. However less is known about nutritional supplements to attenuated the inflammatory/immunological response to training stress.

Probiotic bacteria are defined as live food ingredients beneficial to the host's health. Numerous health benefits have been attributed to probiotics, including effects on gastrointestinal tract function and disease, immune function, hyperlipidemia, hypertension, and allergic conditions. Studies in the literature on the ergogenic effect of probiotics in athletes are still scarce today. this study aims to explore the potential role of probiotics on performance, recovery from fatigue and immune function during intensive period of training.

Enrollment: 16 estimated patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 25-55 years
• Body mass index:> 18 and <30 kg / m2
• Stable body weight for at least 3 months
• regular practice of physical activity for at least 2 years

Exclusion criteria

• Chronic diseases (cardiovascular, hepatic, respiratory, cancer)
• Acute inflammatory states, infections or other pathologies
• Regular use of probiotics
• Use or treatment with steroids (within the previous 3 months)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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16 participants in 2 patient groups, including a placebo group

Probiotics

Experimental group

Description:

participants will train for 15 days while consuming the dietary supplement. During the last 8 days the intensity of training will increase to induce overreaching.

Treatment:

Dietary Supplement: probiotics

Placebo

Placebo Comparator group

Description:

participants will train for 15 days while consuming the dietary supplement. During the last 8 days the intensity of training will increase to induce overreaching.

Treatment:

Dietary Supplement: placebo