Probiotics as Adjunct to Non Surgical Periodontal Therapy for Pregnant Women Oral Health

University of Pavia

Status: Completed

Conditions: Periodontal Diseases

Treatments: Other: Biorepair Toothpaste + Mousse; Other: Biorepair Toothpaste

Study type: Interventional

Funder types: Other

Identifiers

NCT05400538

2022-PREGNANCY

Details and patient eligibility

About

The aim of the present study is to evaluate the use of probiotics in domiciliary oral hygiene procedures in pregnant women.

Patients consenting to participate to the study will undergo periodontal evaluation at the baseline (T0). Then, professional dental hygiene will be performed. Patients will be randomly assigned to:

• Trial group: home oral application of Biorepair Peribioma Toothpaste + Biorepair Peribioma mousse twice a day
• Control group: home oral application of Biorepair Peribioma Toothpaste

Patients will be evaluated after 1 month (T1), 3 (T2) and 6 (T3) months.

Full description

The aim of the present study is to evaluate the use of probiotics in domiciliary oral hygiene procedures in pregnant women.

Patients consenting to participate to the study will undergo periodontal evaluation at the baseline (T0). Then, professional dental hygiene will be performed. Patients will be randomly assigned to:

• Trial group: home oral application of Biorepair Peribioma Toothpaste + Biorepair Peribioma mousse twice a day
• Control group: home oral application of Biorepair Peribioma Toothpaste

Patients will be evaluated after 1 month (T1), 3 (T2) and 6 (T3) months, the following indexes will be assessed: Probing Pocket Depth, Bleeding on Probing (percentage), Clinical Attachment Loss, Gingival recession, Plaque Control Record, Modified Gingival Index, Papillary Marginal Gingival Index.

Enrollment: 30 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• women at the 4th month of pregnancy

Exclusion criteria

• presence of cardiac pacemaker
• neurological and psychiatric diseases
• patients taking bisphosphonates during the previous 12 months from the beginning of the study
• patients undergoing anticancer therapy.
• patients with poor compliance.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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30 participants in 2 patient groups

Trial group

Experimental group

Description:

Biorepair Toothpaste + Mousse domiciliary use

Treatment:

Other: Biorepair Toothpaste + Mousse

Control group

Active Comparator group

Description:

Biorepair Toothpaste domiciliary use.

Treatment:

Other: Biorepair Toothpaste