Probiotics for Preterm Infants

Ankara City Hospital

Status: Not yet enrolling

Conditions: Preterm Infant Feeding Outcomes; Probiotic

Treatments: Dietary Supplement: Bifidobacteria; Dietary Supplement: Probiotic mix preparation

Study type: Observational

Funder types: Other

Identifiers

NCT06885944

ABSH-Neo-Pro1

Details and patient eligibility

About

Probiotics will be used for preterm infants under 32 weeks of gestation and under 1500 g birthweight. Our aim was to investigate the effects of probiotics for stable preterm infants after extubation and who reached full enteral feeding. There are some hesitations among care-givers to start probiotics early due to safety issues although there are many positive effects of these products reported int the literature.

Full description

Our study included premature babies with a birth weight of less than 1500 grams, born at less than 32 weeks of gestation, and without congenital anomalies.

Approval was obtained from the hospital's clinical research ethics committee before starting the study. The decision to start probiotics was made when these premature babies were fully enteral fed. The study design was created as a cohort and case-control study (No randomisation). When clinicians decided to start probiotic support for premature babies with good general health and no additional problems, probiotics were added to the baby's order.

Enrollment: 100 estimated patients

Sex: All

Ages: 7 days to 3 months old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: <32 weeks, <1500 g birthweight -

Exclusion Criteria: Congential anomalies, still parenteral feeding, BW<800 gr and <23 weeks of GA

Trial design

100 participants in 1 patient group

Group 1

Description:

Preterm infants receiving probiotics

Treatment:

Dietary Supplement: Probiotic mix preparation

Dietary Supplement: Bifidobacteria