Probiotics in the Treatment of Irritable Bowel Syndrome

Islamic Azad University, Najafabad Branch

Status and phase: Completed; Phase 3; Phase 2

Conditions: Irritable Bowel Syndrome

Treatments: Drug: Placebo; Drug: Lactol

Study type: Interventional

Funder types: Other

Identifiers

NCT01837485

15010101882058

Details and patient eligibility

About

Some evidences have shown that probiotics are effective in the treatment of irritable bowel syndrome. Because few evidences are available in our population, we investigated if probiotics are effective in our patients as well. We hypothesize that the probiotic Lactol which contains Lactobacillus Sporogenes reduces the symptoms of irritable bowel syndrome.

Enrollment: 82 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age between 18 and 65
• diagnosis of IBS based on the Rome III criteria
• willingness to participate

Exclusion criteria

• receiving other probiotics compound during the study
• receiving antibiotics during the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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82 participants in 2 patient groups, including a placebo group

Lactol

Experimental group

Treatment:

Drug: Lactol

Placebo

Placebo Comparator group

Treatment:

Drug: Placebo