Probiotics Regulates Skin Care in Children

Chang Gung Medical Foundation

Status: Enrolling

Conditions: Children; Probiotics; Skin Care

Treatments: Dietary Supplement: Probiotics Bifidobacterium animalis subsp. lactis CP-9; Dietary Supplement: Probiotics Lactobacillus salivarius AP-32; Dietary Supplement: Probiotics Lactobacillus rhamnosus LGG; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT05005611

XPRPG8L0021~22

Details and patient eligibility

About

Probiotics, a component that is generally referred to as a living microorganism or a microorganism present in a host. Most studies have shown that probiotics can regulate immune function in the body. Many studies have attempted to understand whether the use of probiotics can prevent allergic diseases or not.

Enrollment: 148 estimated patients

Sex: All

Ages: 1 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Estimated by PI.

Exclusion criteria

• Be allergic to medicine
• Take medicine like immune inhibition, or steroid injection in two weeks
• Participate in another clinical research or immune therapy in one month
• Have severe disease
• Inappropriate for this trial judged by PI

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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148 participants in 4 patient groups, including a placebo group

Placebo

Placebo Comparator group

Treatment:

Dietary Supplement: Placebo

Probiotics Lactobacillus salivarius AP-32

Experimental group

Treatment:

Dietary Supplement: Probiotics Lactobacillus salivarius AP-32

Probiotics Bifidobacterium animalis subsp. lactis CP-9

Experimental group

Treatment:

Dietary Supplement: Probiotics Bifidobacterium animalis subsp. lactis CP-9

Probiotics Lactobacillus rhamnosus LGG

Experimental group

Treatment:

Dietary Supplement: Probiotics Lactobacillus rhamnosus LGG