Procalcitonin Level as a Surrogate for Catheter-related Blood Stream Bacteremia Among Hemodialysis Patients

Benha University

Status: Completed

Conditions: Hemodialysis Catheter Infection

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03039777

17a1b

Details and patient eligibility

About

Hemodialysis patients frequently develop catheter-related blood stream bacteremia (CRBSI). Procalcitonin is a marker of sepsis in bacterial infection. this study for detection of its role as a surrogacy marker in CRBSI.

Full description

Catheter-related blood stream bacteremia is common among hemodialysis patients. Clinically, fever and/or rigors with laboratory indicator of inflammation as leucocytosis and elevated c-reactive protein level are considered as markers for CRBSI before blood culture results became available.

Procalcitonin is a valid indicator of sepsis. In this study, Procalcitonin level will be measured in any patient with suspected CRBSI and correlation will be tested for proved CRBSI by blood cultures.

Enrollment: 28 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hemodialysis patients with a dialysis catheter
• signs suggestive of CRBSI: fever/chills or leucocytosis with no other site of infection.
• Informed consent signed to be enrolled in the study

Exclusion criteria

• Patient with identified cause of fever other than CRBSI