Procalcitonin Ratio's Impact on the Decision Upon On-demand Relaparotomy in Septic Peritonitis

CHIR-Net

Status: Completed

Conditions: Secondary Peritonitis After Intestinal Perforation

Study type: Observational

Funder types: NETWORK

Identifiers

NCT01768936

TUM-PCT-1

PCTRatio Reevaluation (Other Identifier)

Details and patient eligibility

About

Procalcitonin (PCT) serum levels are monitored in patients with secondary peritonitis after initial operative focus elimination to investigate the PCT ratio's impact on decision-making for or against early relaparotomy in the on-demand relaparotomy concept of secondary septic peritonitis.

Enrollment: 234 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age >18 years
• necessity for operative intervention to eliminate an infectious peritoneal / abdominal focus after organ perforation
• abdominal sepsis according to the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definition

Exclusion criteria

• pregnancy
• immunosuppressive medication

Trial design

234 participants in 2 patient groups

eliminated infectious abdominal focus

persisting/progressing infectious abdominal focus