Procalcitonin Use in Pneumonia Patients in the Critical Care Setting

Mayo Clinic

Status: Completed

Conditions: Pneumonia

Treatments: Other: Use of procalcitonin as biomarker to guide therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT01788488

12-008835

Details and patient eligibility

About

The goal of the study is to determine the impact of procalcitonin (PCT)-guided therapy on duration of antibiotic therapy in critical care unit (CCU) patients with suspected pneumonia at Mayo Clinic Health System Eau Claire.

Enrollment: 134 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years old
• admitted to critical care unit
• placed on pneumonia protocol

Exclusion criteria

• patients who received outpatient antibiotic therapy within previous 21 days

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

134 participants in 2 patient groups

Standard Therapy

No Intervention group

Procalcitonin-guided therapy

Experimental group

Description:

Procalcitonin levels will be measured to determine when it is appropriate to discontinue antibiotic therapy.

Treatment:

Other: Use of procalcitonin as biomarker to guide therapy