Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department

United States Naval Medical Center, Portsmouth

Status: Withdrawn

Conditions: Acute Migraine Headache

Treatments: Drug: prochlorperazine and benadryl IV; Drug: Imitrex SubQ, saline IV

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT00573599

P06-050

Details and patient eligibility

About

ED patients with acute migraine will be randomized to either prochlorperazine and Bendaryl OR imitrex. VAS for pain will be monitored, along with side effects. Primary outcome measure is improvement in pain scales between the groups.

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute migraine headache

Exclusion criteria

• Pregnant
• Hypertension
• Chest pain
• < 18
• Allergy to any of the meds

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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0 participants in 2 patient groups

1

Experimental group

Description:

prochlorperazine and benadryl IV, saline subQ

Treatment:

Drug: prochlorperazine and benadryl IV

2

Active Comparator group

Description:

imitrex SubQ, saline IV

Treatment:

Drug: Imitrex SubQ, saline IV