Professional and Personal Toxic Exposure in Systemic Sclerosis : Type, Intensity and Probability of Exposition (VISSEXPOSITION)

University Hospital of Bordeaux

Status: Completed

Conditions: Systemic Sclerosis

Treatments: Behavioral: Questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT03543956

CHUBX 2018/09

Details and patient eligibility

About

Systemic Sclerosis (SSc) is an inflammatory chronic disease that can lead to structural damage and handicap. The SSc physiopathology is multifactorial, including genetic and environmental risk factors. The identification of environmental factors implication is crucial to understand the SSc mechanism, and improves the diagnosis and the treatment of the disease.

Full description

Studies show that the risk associated with high cumulative exposure to silica and organic solvents appears to be strongly increased in SSc. Moreover, exposure to silica is associated with a specific type of SSc phenotype with a worse prognosis. However, the type, intensity and probability of these expositions are unknown.

The aim of the study is to precisely determine type, intensity and probability of toxic substances exposition in Systemic Sclerosis patients through an auto-questionnaire and integration of these data in a computer matrix.

Enrollment: 226 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged over 18 years old
• Speaking and understanding French language
• Being informed about the study and having given his consent
• Affected by SSc according to EULAR 2013 criteria

Exclusion criteria

• Patient under tutorship
• Patient who refuse to participate

Trial design

226 participants in 1 patient group

Systemic Sclerosis patient

Description:

patients affected by SSc according to EULAR 2013 criteria

Treatment:

Behavioral: Questionnaire