Profiling the Endocannabinoid Response to Hedonic Eating (Lekkere trek)

Wageningen University

Status: Completed

Conditions: Obesity; Food Preferences

Treatments: Other: Food palatability

Study type: Interventional

Funder types: Other

Identifiers

NCT03113474

NL51830.081.14

Details and patient eligibility

About

Study into the endocannabinoid response to consuming a palatable versus a neutral food.

Enrollment: 25 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy (self-report)
• Dutch
• Evaluating one of the used foods as palatable
• Evaluating one of the used foods as neutral
• Hb value between 8.1 and 11.0 mmol/L at screening

Exclusion criteria

• restraint eating
• lack of appetite
• difficulties eating/swallowing
• endocrine disorders
• energy restricted diet two months prior to study
• weight change > 5 kg in two months prior to study
• stomach or bowel disease
• taste or smell disorders (self-report)
• not consuming foods used in the study
• smoking > 1 cigarette per day
• drinking > 21 units alcohol per week

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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25 participants in 2 patient groups

Palatable-neutral

Experimental group

Description:

Participants are exposed to palatable food in the first test session, and to the neutral food in the second test session.

Treatment:

Other: Food palatability

Neutral-palatable

Experimental group

Description:

Participants are exposed to neutral food in the first test session, and to the palatable food in the second test session.

Treatment:

Other: Food palatability