Progesterone Levels and Pregnancy Results

Ufuk University

Status: Unknown

Conditions: Pregnancy Complications; Pregnancy Loss; Pregnancy Preterm

Treatments: Diagnostic Test: amniocentesis

Study type: Observational

Funder types: Other

Identifiers

NCT04400149

amniotic fluid progesteron

Details and patient eligibility

About

The aim of this study is to evaluate the amniotic fluid and serum progesterone level and pregnancy outcome

Full description

Studies have investigated the relationship between maternal serum progesterone level and low birth weight baby birth, hypertensive disorders of pregnancy, and early pregnancy bleeding. In some cases, patients are supported by oral or vaginal progesterone treatments during pregnancy. We also measure the relationship between maternal serum progesterone by measuring the level of amnion progesterone; We aimed to analyze the effects on pregnancy outcomes by observing preterm birth, premature rupture of membranes, low birth weight, baby gender, maternal problems that may occur during pregnancy, fetal problems.

Enrollment: 100 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Singleton pregnancy
• Women who did not receive progesterone treatment during pregnancy

Exclusion criteria

• Women who receive progesterone treatment during pregnancy
• multiple pregnancies
• Diagnosed hypertension, diabetes mellitus, kidney disease, heart disease, liver disease

Trial design

100 participants in 2 patient groups

1

Description:

amniotic fluid progesterone (this group will be evaluated by the amniotic fluid which was received via amniocentesis). This group consisted of pregnant women who had high risk in the antenal test and give consent to perform amniocentesis. Notwithstanding, amniocentesis detects chromosome abnormalities, neural tube defects, and genetic disorders for the fetuses. İn a routine amniocentesis, 1-2 ml amniotic fluid which was taken in the first place was discarded in order to prevent maternal contamination. Then 15-20 ml amniotic fluid was taken from all of the patients to diagnose genetic disorders of the fetuses. İn this study we evaluate the amniotic fluid progesterone in this 1-2 ml amniotic fluid which was discarded and throw away. Therefore, we are not performing an extra invasive procedure for pregnant women

Treatment:

Diagnostic Test: amniocentesis

2

Description:

serum progesterone (this group consisted of the pregnant women who have amniocentesis procedure and blood samples were taken in the same procedure )

Treatment:

Diagnostic Test: amniocentesis