Progesterone on the Day of Ovulation Induction is Associated With Pregnancy Outcome (ProgBBN)

Bollmann Bruckner Noss

Status: Completed

Conditions: Female Infertility

Study type: Observational

Funder types: Other

Identifiers

NCT01426152

Prog2006-2011

BBN (Other Identifier)

Details and patient eligibility

About

Progesterone levels measured in blood/serum of patients on the day of ovulation induction following controlled ovarian stimulation for in vitro fertilization may be associated with pregnancy outcome. The hypothesis is that higher progesterone levels are associated with lower implantation rates due to changes in the endometrial receptivity.

Enrollment: 2,555 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• IVF/ICSI following controlled ovarian stimulation
• progesterone measured on the day of ovulation induction
• informed consent

Exclusion criteria

• missing consent

Trial design

2,555 participants in 3 patient groups

Low level progesterone group (1)

Description:

Progesterone \< 1.50 ng/mL on day of ovulation induction

Medium level progesterone group (2)

Description:

Progesterone 1.51-1.99 ng/mL on the day of ovulation induction

High level progesterone group (3)

Description:

Progesterone \> 1.99 ng/mL on the day of ovulation induction