Prognosis of Geriatric Patients 1 Year After Hospitalization for COVID-19 (PROVID-Ger)

Assistance Publique - Hôpitaux de Paris

Status: Not yet enrolling

Conditions: COVID-19

Study type: Observational

Funder types: Other

Identifiers

NCT05261061

APHP211505

IDRCB 2021-A02684-37 (Other Identifier)

Details and patient eligibility

About

Old patients hospitalized in Acute Geriatric Units are characterize by advanced age, frailty, high number of comorbidities, cognitive impairment and loss of functional autonomy. Although, intra-hospital mortality in geriatric population (out of COVID) is low (6%) the long-term prognosis is often worse (30 to 60% of loss of autonomy and 30% of one-year mortality among hospital survivors).

For geriatric patients with COVID19, intra-hospital mortality is higher than in younger Covid patients (1), but also higher than in geriatric patients outside the Covid context (30 vs 6% (2, 3)). Our hypothesis is that geriatric patients surviving hospitalization for COVID-19 have a worse vital and functional prognosis at 12 months than geriatric patients surviving hospitalization for another medical reason.

Full description

Old patients hospitalized in Acute Geriatric Units are characterize by advanced age (average 85 years), frailty, high number of comorbidities, cognitive impairment and loss of functional autonomy.These particular state leads to multiple decompensations and the reason for initial hospitalization is often only the "tip of the iceberg". Although, intra-hospital mortality in geriatric population (out of COVID) is low (6%) the long-term prognosis is often worse (30 to 60% of loss of autonomy and 30% of one-year mortality among hospital survivors).

For geriatric patients with COVID19, intra-hospital mortality is higher than in younger Covid patients (1), but also higher than in geriatric patients outside the Covid context (30 vs 6% (2, 3)). This excess mortality is all the more surprising as these patients seem to have fewer comorbidities than those usually hospitalized in acute geriatric units.

Our hypothesis is that geriatric patients surviving hospitalization for COVID-19 have a worse vital and functional prognosis at 12 months than geriatric patients surviving hospitalization for another medical reason.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 75+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >=75 years
• Hospitalized for medical reason in acute geriatric unit
• Alive at hospital discharge

Exclusion criteria

• Patients hospitalized for surgical reason
• Patients under legal protection
• Patient refusal

Trial design

1,000 participants in 2 patient groups

Old patients hospitalized in acute geriatric unit

Old patients hospitalized for other medical diagnosis in acute geriatric unit