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Prognosis of Hematological Cancer Patient Underwent Mechanical Ventillation

M

Mansoura University

Status

Completed

Conditions

Hematological Malignancy
Mechanical Ventilation
Acute Respiratory Failure

Treatments

Procedure: Mechanical ventilation

Study type

Observational

Funder types

Other

Identifiers

NCT02562105
15.05.42

Details and patient eligibility

About

This observational cohort aimed to re-evaluate the outcome of hematologic cancer patients admitted to the intensive care unit of Mansoura oncology center through a cohort study as regards their need for mechanical ventilation during two years.

Full description

It has been believed for many years that the scene of cancer patients requiring mechanical ventilation is frustrating. The needed life support measures drain much of health resources and add a significant burden on the patient's family. Many factors have been responsible for the high mortality rates among hematologic cancer patients admitted to intensive care unit. Among of these factors, the invasive treatments that are frequently employed in today's intensive care unit. These procedures give chance for development of severe infection and multiple organ failure which are common events in immune-compromised patients (e.g. neutropenia) and in those exposed to chemotherapy. The most common form of organ failure in those patients is acute respiratory failure which is a major predictor of mortality in that population. The prognosis of such failure may vary depending on its causes and severity, co morbidity, associated acute organ failure and characters of the underlying malignancy. After the recent advances in the field of intensive care and shedding light on the benefits of the noninvasive ventilation in immune-compromised patients, the overall survival rate of cancer patients admitted to intensive care unit are improving.

Enrollment

50 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Critical ill hematological cancer patient
  • Requiring mechanical ventilation

Exclusion criteria

  • Patients with acute coronary syndrome.
  • Patients with cancer remission more than 5 years.

Trial design

50 participants in 1 patient group

Mechanical ventilation
Description:
requiring mechanical ventilation at admission to ICU for one day or more during the study period
Treatment:
Procedure: Mechanical ventilation

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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