Prognosis of Patients Who Presented With a State of Extreme Agitation. (AGICOHORT)

Assistance Publique - Hôpitaux de Paris

Status: Enrolling

Conditions: Emergence Delirium

Study type: Observational

Funder types: Other

Identifiers

NCT05632419

P220382

Details and patient eligibility

About

The main objective is to assess the 6-month prognosis of patients who presented with extreme agitation in the emergency room.

The primary endpoint is the 6-month mortality of agitated patients.

Full description

Emergency services are confronted with emergency situations characterized by patients who are victims of significant agitation, in particular states of extreme agitation "excited delirium syndrome", which is constantly increasing and which seems to be associated with morbidity and mortality not negligible.

Patients meeting the inclusion and non-inclusion criteria are included on admission to the emergency room.

An evaluation at H1 and at the end of hospitalization is carried out. The patient is contacted by telephone at M1, M3 and M6.

The inclusion period is 24 months The duration of participation (treatment + follow-up) is 6 months The total duration is 30 months.

The research is multicentric and national with the participation of 8 centres.

Enrollment: 608 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Agitated patient with the presence of three major criteria, namely,
• restlessness
• insensitivity to pain
• tachypnea (fr>20)

and the presence of a minor criterion among

• sweating
• skin hyperthermia
• non-compliance with law enforcement
• tirelessness
• unusual strength
• inappropriate clothing, nudity

Exclusion criteria

• patient age < 18 years
• head trauma
• pregnancy
• detained
• other obvious causes of pain leading to restlessness (renal colic, migraines, etc.)