Prognosis of Right Ventricular Dysfunction Assessed by Speckle Tracking in Postoperative Thoracic Surgery (SPECKLETHO)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Right Ventricle; Thoracic Surgery

Treatments: Other: transthoracic echocardiography (TTE)

Study type: Interventional

Funder types: Other

Identifiers

NCT05060302

PI2021_843_0030

Details and patient eligibility

About

In postoperative thoracic surgery (lobe resection, pneumonectomy or wedge resection), cardiovascular complications are the most frequent (10 to 15%) with a significant morbi-mortality rate. Right ventricular (RV) dysfunction is a complication that can be multifactorial in post thoracic surgery. The RV longitudinal shortening fraction (RV-LSF) is a new 2D-STE parameters able to more accurately detect patients with RV dysfunction compared to conventional echocardiographic parameters.

This project is a single-center, prospective, interventional study of patients hospitalized at the Amiens University Hospital for scheduled thoracic surgery. TTE is performed preoperatively, at day 2 and day 15 following the thoracic surgery. Echocardiographic parameters will be measured by an echocardiographic expert in offline with a dedicated software. MACE criteria will be collected at day 2, day 15 and day-30 following the thoracic surgery.

Enrollment: 164 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patient (>18 years)
• Patient hospitalized at the Amiens University Hospital for scheduled thoracic surgery (lobectomy, pneumonectomy, wedge resection).
• Surgery by thoracotomy or video-assisted thoracic surgery
• Information of the patient and collection of his non-opposition

Exclusion criteria

• Patient with poor echogenicity on TTE not allowing evaluation of 2D-STE or conventional parameters of the RV.
• Patient with a rapid supraventricular rhythm disorder (HR > 100) at the time of TTE
• Patient under mechanical ventilation
• Patient under extracorporeal membrane oxygenation
• Patients under guardianship or legal protection
• Patients whose clinical condition does not allow for their non-opposition
• Pregnant women

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)