Prognostic and Diagnostic Value of Biomarkers and Cardiac Functional Parameters in Patients With Chronic Heart Failure

Shanghai Jiao Tong University School of Medicine

Status: Enrolling

Conditions: Chronic Heart Failure

Treatments: Other: Observational study

Study type: Observational

Funder types: Other

Identifiers

NCT02776384

RJH-20151127

Details and patient eligibility

About

The study aims to investigate whether disease progression in patients with chronic heart failure (CHF) can be assessed by new biomarkers, and determine their diagnostic value. The study also intends to describe comparison of echocardiography with cardiopulmonary function test in CHF patients, and relating these cardiac functional parameters to clinical outcome.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years
• with symptoms and signs in NYHA Ⅱ~Ⅳ
• with cardiac structural changes confirmed by echocardiography

Exclusion criteria

• with other severe diseases combined and will be alive for less than 12 months
• hard to participate in the investigation or accept the follow-up visits
• pregnant or lactating women
• during the acute phase of ST-elevation acute myocardial infarction, stroke, severe infection and other critical conditions

Trial design

1,000 participants in 1 patient group

chronic heart failure

Description:

patients who are diagnosed with chronic heart failure with either preserved or reduced ejection fraction

Treatment:

Other: Observational study