Prognostic and Predictive Biomarkers of Therapeutic Response in Pancreatic Tumors (PACAomics)

Institut Paoli-Calmettes

Status: Completed

Conditions: Pancreatic Tumor

Treatments: Procedure: suspected pancreatic tumor

Study type: Interventional

Funder types: Other

Identifiers

NCT01692873

PACAomics / IPC 2011-004

Details and patient eligibility

About

Pancreatic cancer is among the most serious human neoplasia and the most difficult to treat.

Most patients present at diagnosis a non resectable, locally advanced or metastatic disease, with a median survival of 12 month.

The aim of this study is the identification of diagnosis biomarkers, predictive of the therapeutic response.

This project investigate the use of molecular analyses applied to pancreatic tumor cells collected by microbiopsy under ultrasound-endoscopy, and blood cells.

Enrollment: 274 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Suspicion of pancreatic adenocarcinoma
• Patient > 18 years old
• Social Security affiliation
• Signed informed consent

Exclusion criteria

• Patient in emergency situation
• Major person being the object of a legal protective measure or unable to express its consent

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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274 participants in 1 patient group

suspected pancreatic tumor

Experimental group

Description:

Realization of pancreatic tumor biopsy and blood samples

Treatment:

Procedure: suspected pancreatic tumor