Prognostic Factors for Descending Necrotizing Mediastinitis Development in Deep Space Neck Infections

Clinical Center of Vojvodina

Status: Completed

Conditions: Inflammation; Mediastinitis; Infection; Neck Abscess

Treatments: Other: treatment of infection

Study type: Observational

Funder types: Other

Identifiers

NCT04865003

1208983

Details and patient eligibility

About

Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM development in deep space neck infections.

Full description

Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM development in deep space neck infections. The study enrolled patients admitted to the Emergency Center of Vojvodina with the diagnosis of multispace DNI with or without DNM either as the primary diagnosis or with discharged diagnosis after surgical treatment during 7-years period. The data were obtained from patient medical records.

Enrollment: 289 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients admitted to the hospital due to deep neck infection affecting two or more spaces with or without descending necrotizing medioastinitis
• complete diagnosis and treatment data available from medical charts

Exclusion criteria

• incomplete medical data
• infection confined to one deep neck space
• patients treated under local anesthesia
• patients with superficial skin infections
• iatrogenic infections
• infected tumors

Trial design

289 participants in 2 patient groups

DNI group

Description:

patients with infection of two or more deep neck spaces (DNI group)

Treatment:

Other: treatment of infection

DNI + DNM group

Description:

patients with infection of two or more deep neck spaces with secondary descending necrotizing mediastinitis (DNI + DNM group)

Treatment:

Other: treatment of infection