Prognostic Impact of PMI in Stable CAD Undergoing PCI

Fudan University

Status: Unknown

Conditions: Coronary Artery Disease; Percutaneous Coronary Intervention; Periprocedural Myocardial Injury

Study type: Observational

Funder types: Other

Identifiers

NCT04239404

PMI-CAD-PCI

Details and patient eligibility

About

This is a single-center, observational, prospective study. This study aims to observe the effect of periprocedural myocardial injury on cardiovascular events in patients undergoing elective percutaneous coronary intervention, and to detect the levels of serum inflammatory factors before and after intervention to predict the occurrence of periprocedural myocardial injury and its association with cardiovascular events.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• underwent elective coronary stenting
• patients permit informed consents

Exclusion criteria

• acute STEMI
• NYHA class III-IV heart failure
• moderate-to-severe valvular disease
• missing post-PCI troponin results
• active infection, respiratory failure
• liver dysfunction (liver enzyme >3xURL or bilirubin >2xURL),
• malignancy and systemic connective tissue disease
• unable to get a informed consents

Trial design

2,000 participants in 2 patient groups

PMI

non-PMI