Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty (IPPVM)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Mitral Valve Prolapse; Mitral Plasty

Study type: Observational

Funder types: Other

Identifiers

NCT03113552

PI2013_843_0002

Details and patient eligibility

About

Mitral insufficiency (MI) accounts for 24% of adult valvulopathies and affects 7% of subjects older than 75 years. They are the second leading cause of valvulopathy in Europe. The most common etiology is the associated valvular prolapse. Mitral surgery remains the reference treatment for symptomatic MI. The success of this procedure depends on the mitral valve geometry and the location of the prolapse. The site of the prolapse, whether monovalvular, localized to the posterior or anterior leaflet, or bivalvular, influences the possibilities and probably the long-term results of the plasty.

Enrollment: 1,500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients operated between 1988 and 2011
• Presence of a valvular prolapse diagnosed by echocardiography
• Possibility of a complete clinical evaluation at the time of the initial echocardiography

Exclusion criteria

• Ischemic MI (including papillary muscle rupture)
• Presence of significant aortic valvulopathy, mitral valvular stenosis or congenital disease
• History of cardiac surgery