Prognostic Model of Elderly Hodgkin Lymphoma in China

Tianjin Medical University

Status: Active, not recruiting

Conditions: Hodgkin Lymphoma

Study type: Observational

Funder types: Other

Identifiers

NCT07374068

TCH-HL-ELDER-2025

Details and patient eligibility

About

This multicenter observational cohort study is based on a patient registry designed to systematically collect uniform real-world clinical data from elderly patients with Hodgkin lymphoma (HL) in China. The registry captures demographic characteristics, disease features, laboratory parameters, treatment patterns, and longitudinal survival outcomes to support predefined scientific objectives.

The primary analysis uses retrospectively collected registry data, with prospectively accrued data incorporated for external validation of a prognostic prediction model. This registry-based study aims to improve risk stratification and inform individualized clinical decision-making for elderly patients with HL in routine clinical practice.

Enrollment: 400 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥60 years
• Histologically confirmed Hodgkin lymphoma, including classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma
• Treatment-naïve patients who have not received prior anti-Hodgkin lymphoma therapy
• Availability of complete clinical, pathological, and follow-up data

Exclusion criteria

• Presence of other malignant tumors
• Severe hepatic or renal dysfunction (Child-Pugh class C or estimated glomerular filtration rate <30 mL/min)
• Missing more than 20% of required clinical data

Trial design

400 participants in 1 patient group

Elderly patients with Hodgkin lymphoma

Description:

Observational Cohort