Prognostic Score To Predict Major Complications After Pancreaticoduodenectomy

Università Vita-Salute San Raffaele

Status: Completed

Conditions: Pancreatic Neoplasm

Treatments: Procedure: Pancreaticoduodenectomy

Study type: Observational

Funder types: Other

Identifiers

NCT01278381

PANCREATICODUODENECTOMY_SCORE

Details and patient eligibility

About

Pancreaticoduodenectomy (PD) still carries a high rate of severe postoperative complications. No score is currently available to help identify the patient's surgical risk. The purpose of this study was to develop and validate a prognostic score to predict major postoperative complications after PD.

Full description

The investigators prospectively collected in an electronic database preoperative, intraoperative and outcome data of 700 patients undergoing PD in our Institution from 2002 to 2010. The investigators used a multivariate logistic regression analysis to create a new score to predict severe complications defined as Clavien-Dindo classification III, IV and V. The score was developed using a random two-thirds of the population (469 patients), and was then validated and calibrated in the remaining third of the patients (231).

Enrollment: 700 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing pancreaticoduodenectomy in our Institution

Exclusion criteria

• Metastatic disease
• Patient not suitable for surgery

Trial design

700 participants in 1 patient group

Pancreaticoduodenectomy (PD)

Description:

Patients undergoing PD from 2002 to 2010

Treatment:

Procedure: Pancreaticoduodenectomy