Prognostic Value of Capillary Lactatemia in Potentially Severe Polytrauma Patients (CLAT)

Centre Hospitalier Universitaire de Nice

Status: Not yet enrolling

Conditions: Polytrauma

Treatments: Biological: capillary blood sampling

Study type: Interventional

Funder types: Other

Identifiers

NCT06969404

24-AOI-05

Details and patient eligibility

About

Nowadays, the tools available to assess the severity of a polytrauma patient in the pre-hospital setting (vital parameters, shock index, MGAP score, Vittel criteria) have their limitations and are sometimes subjective. To date, there are no objective, practical and reproducible tools for triaging these patients. Venous lactataemia also appears to be predictive of poor outcome in severe trauma. However, there are no studies in the literature on capillary lactataemia, which would indicate the potential severity of a polytrauma patient in the pre-hospital setting. However, it is an easily performed, risk-free assay, the results of which can be obtained rapidly at the scene of the accident. The aim of this project is to confirm that, like venous lactataemia, capillary lactataemia can be useful in the pre-hospital phase for predicting a patient's poor outcome. Incorporating this assay into the assessment of potentially severe polytrauma patients in the pre-hospital phase could improve the predictive value of clinical and contextual data and thus enable better referral and management of these patients.

Enrollment: 550 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient over 18 years of age

• Presenting a potentially serious pre-hospital trauma defined by:

  o A road accident or a fall of more than 2 metres

• Requiring the dispatch of a SMUR 06 team (mobile emergency and resuscitation service)

• And transferred to an emergency facility in the Alpes Maritimes with medical assistance.

• Consent signed (by the patient or a relative) after the event if it is not possible to sign immediately.

• Pregnant women may also take part in the study without any risk to themselves or their child.

Exclusion criteria

• Patients with isolated peripheral limb trauma (wrist, elbow, knee, ankle, shoulder)
• Patients under legal protection (guardianship, curatorship)
• Patients in cardiorespiratory arrest when taken into care by the SMUR (emergency medical services)

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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550 participants in 1 patient group

polytrauma patient

Other group

Description:

capillary blood sampling

Treatment:

Biological: capillary blood sampling