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Prognostic Value of Progesterone for In Vitro Fertilization (IVF) Outcome (PROG2)

A

Aristotle University Of Thessaloniki

Status

Completed

Conditions

Subfertility

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

This observational study attempts to investigate the potential role of serum progesterone levels on the day of hCG administration (thus, the end of the follicular phase) on the probability of pregnancy, in patients undergoing IVF with the use of GnRH antagonists and recombinant gonadotrophins.

There has been evidence, that increased serum levels of progesterone are associated with a decreased probability of pregnancy after IVF.

This study will attempt to explore the role of progesterone on the outcome of IVF, by closely monitoring its levels during the late follicular phase.

Enrollment

130 patients

Sex

Female

Ages

18 to 39 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age < 40 years
  • Basal FSH < 12 IU/L
  • Basal P < 1.6 ng/mL

Exclusion criteria

  • Presence of cystic formations at the ovaries during the basal ultrasound scan (prior the initiation of stimulation)
  • Women with polycystic ovaries syndrome (PCOS)
  • Women with Stage III-IV Endometriosis
  • Women with a pathological condition of the adrenal glands

Trial design

130 participants in 1 patient group

Patients undergoing IVF with rFSH and GnRH antagonists

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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